In the main event, lightweight Islam Makhachev faces off with Bobby Green, who replaced an injured Beneil Dariush on short notice after an impressive showing at UFC 271. Makhachev is tied with Dariush at No. 4 on the MMA Fighting Global Rankings, while Green is unranked.
In the co-main, middleweights Misha Circkunov and Wellington Turman square off.
Check out the UFC Vegas 49 results below.
Main card (ESPN+ at 7 p.m. ET)
Islam Makhachev vs. Bobby Green
Misha Cirkunov vs. Wellington Turman
Preliminary Card (ESPN+ at 4 p.m. ET)